Scientists are bringing back woolly mammoths through mice?

UPDATED: Mar 6, 2025 17:49 IST

In a significant breakthrough in de-extinction science, Texas-based bioengineering company Colossal Biosciences has successfully created genetically modified mice with thick, woolly coatsdubbed "woolly mice"as a step towards reviving the extinct woolly mammoth.

The mice, which appear normal apart from their long, dense fur, were developed using mammoth genes that scientists have identified as key to cold tolerance. Colossal Biosciences' CEO and Co-Founder, Ben Lamm, described the achievement as an important milestone in the company’s goal of bringing the prehistoric giant back to life.

"We actually engineered mouse equivalents of mammoth genes in a healthy way and produced what we believe are cold-tolerant, woolly, phenotype-driven mice," Lamm announced following the breakthrough.

The first of the genetically modified mice were born in October 2024, with a total of 38 successfully delivered. According to Lamm, all were "happy and healthy," with no unexpected consequences apart from their enhanced cuteness.

Colossal Biosciences argues that de-extinction technology could play a crucial role in biodiversity conservation. "We are at risk of losing up to 50 per cent of biodiversity by 2050 if no action is taken. We know modern conservation works, but not at the speed required to counteract habitat destruction and species extinction," Lamm stated.

The company’s Chief Science Officer, Beth Shapiro, emphasised the broader ecological significance of the work. "Ecosystems with greater biodiversity are more resilient. By re-establishing these interactions and preventing extinctions, we aim to stabilise ecosystems and protect species today."

Beyond the woolly mammoth, Colossal Biosciences is also working to bioengineer other extinct species, including the Tasmanian tiger and the dodo, in a bid to restore lost biodiversity and enhance ecosystem resilience.